Key result
A left ventricular global longitudinal strain value < -10.8 predicted the development of LV remodeling with 80% sensitivity and 86% specificity in patients after acute coronary syndrome.
Why the study?
Even a persistently patent infarct-related artery is associated with LV remodeling, prompting evaluation of echocardiographic LV strain imaging to predict LV remodeling after coronary revascularization.
Does global longitudinal strain (GLS) measurement by echocardiography predict left ventricle remodeling in patients undergoing PTCA for acute coronary syndrome?
Observational (n=104)
Does global longitudinal strain (GLS) measurement by echocardiography predict left ventricle remodeling in patients undergoing PTCA for acute coronary syndrome?
Global longitudinal strain assessment by echocardiography in the acute setting can predict adverse LV remodeling after acute coronary syndrome with high sensitivity and specificity.
Answers are grounded in this paper and cite their sources.
May support post-ACS risk stratification; leaves open whether GLS-guided therapy alters remodeling or outcomes.
Background: Even persistently patent infarct-related artery has been shown to be associated with left ventricle (LV) remodeling. The purpose of this study was to evaluate the role of LV strain imaging by echocardiography in predicting LV remodeling in patients undergoing coronary revascularization. Materials and Methods: A total of 104 patients between the ages of 18 and 75 years of age undergoing percutaneous transluminal coronary angioplasty (PTCA) for acute coronary syndrome (ACS) were selected and subsequently followed up for 3 months. Echocardiography was obtained before PTCA and subsequently 3 months later with global longitudinal strain (GLS) measurements. Results: In our study, 24% patients studied developed LV remodeling at 1 month even after clinical, angiographic, and procedural success of percutaneous intervention. A value of LV GLS <−10.8 predicted the development of LV remodeling with 80% sensitivity and 86% specificity with lower values having higher specificity. Conclusions: GLS assessment by echocardiography in the acute setting is feasible and easy to do with no complications and may be used with considerable sensitivity in predicting patients with adverse remodeling after ACSs.
No takes yet. Share an insight, caveat, or question.
Agarwal et al. (2021) conducted an observational in Acute coronary syndrome (n=104). Left ventricular global longitudinal strain (GLS) imaging was evaluated on Development of LV remodeling (80% sensitivity and 86% specificity). A left ventricular global longitudinal strain value < -10.8 predicted the development of LV remodeling with 80% sensitivity and 86% specificity in patients after acute coronary syndrome.
Synapse has enriched 10 related papers. Consider them for comparative context: