October 1, 2000European Journal of BiochemistryOpen Access

G‐protein mediated gating of inward‐rectifier K+ channels

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Population

Mammals (focus on G-protein regulated inward-rectifier potassium channels [GIRK])

Design

Review

Authors

MMMelanie D. MarkRuhr University Bochum SHStefan HerlitzeUniversity Hospitals of the Ruhr-University of Bochum

Discussion

Member takes

Implication

Supports further investigation of GIRK modulators for rate control; leaves open clinical adoption pending prospective trials.

Structured PICO

Population

Mammals (focus on G-protein regulated inward-rectifier potassium channels [GIRK])

This review highlights the physiological importance of GIRK channels, specifically noting the role of GIRK1 and 4 subunits in regulating cardiac rate in the atrial and sinoatrial nodes.

Cite This Study

Mark et al. (2000) studied this question.

synapsesocial.com/papers/6a7c46fd7eebcb99d4a160f4 https://doi.org/10.1046/j.1432-1327.2000.01670.x

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G‐protein mediated gating of inward‐rectifier K+ channels

Discussion

Member takes

Implication

Structured PICO

Cite This Study

G‐protein mediated gating of inward‐rectifier K+ channels

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider