Why the study?
Does exercise-based cardiac rehabilitation reduce cardiac mortality in patients with coronary heart disease, and how much of this reduction is attributable to risk factor improvements?
Population
2984 patients from 19 randomized controlled trials receiving rehabilitation following an acute myocardial…
Comparison
Exercise-only cardiac rehabilitation vs Control group
Design
Meta-analysis
Authors
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Supports exercise-based cardiac rehabilitation in CHD; extends prior evidence by quantifying risk factor mediation of mortality benefit.
Does exercise-based cardiac rehabilitation reduce cardiac mortality in patients with coronary heart disease, and how much of this reduction is attributable to risk factor improvements?
Approximately half of the mortality benefit of exercise-based cardiac rehabilitation in CHD patients is mediated by reductions in major cardiovascular risk factors, particularly smoking.
Taylor et al. (2006) studied this question.
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