Why the study?
Data on the association of cardiovascular health across midlife with depressive symptoms are lacking.
Does better cardiovascular health reduce the risk of incident depressive symptoms in adults?
Population
6980 participants without depressive symptoms from the GAZEL cohort in France
Comparison
Cardiovascular health metrics at intermediate or ideal levels and 7-year change vs lower levels
Design
Prospective community-based cohort study
Follow-up
19 years
Key result
Higher baseline cardiovascular health was associated with a lower risk of incident depressive symptoms (OR per additional metric 0.87; 95% CI 0.84-0.91).
Authors
Loading...
May inform CVH counseling; leaves open whether interventions reduce incident depression.
Cohort (n=6,980)
Does better cardiovascular health reduce the risk of incident depressive symptoms in adults?
Odds Ratio: 0.87 (95% CI 0.84–0.91)
Better baseline cardiovascular health and its improvement over time are associated with a significantly lower risk of developing depressive symptoms in midlife adults.
Sloten et al. (2023) conducted a cohort in Depressive symptoms (n=6,980). Higher cardiovascular health (number of metrics at intermediate or ideal level) vs. Lower cardiovascular health was evaluated on Incident depressive symptoms (CES-D score ≥17 in men or ≥23 in women) (OR 0.87, 95% CI 0.84-0.91). Higher baseline cardiovascular health was associated with a lower risk of incident depressive symptoms (OR per additional metric 0.87; 95% CI 0.84-0.91).