Key result
Following balloon valvuloplasty for pulmonary valve stenosis, 88% of patients developed pulmonary valve regurgitation at a mean follow-up of 4 years, with 64% having mild, 18% moderate, and 6% severe regurgitation.
Why the study?
Does pulmonary valve balloon dilatation lead to moderate or severe pulmonary valve regurgitation in pediatric patients with isolated pulmonary valve stenosis?
Cohort (n=50)
No
Does pulmonary valve balloon dilatation lead to moderate or severe pulmonary valve regurgitation in pediatric patients with isolated pulmonary valve stenosis?
Pulmonary valve regurgitation is a common but generally mild and well-tolerated late finding after balloon valvuloplasty for pulmonary valve stenosis in pediatric patients.
Answers are grounded in this paper and cite their sources.
Pulmonary regurgitation is common yet mostly mild after pediatric balloon valvuloplasty; leaves open long-term progression and intervention thresholds.
BACKGROUND: Pulmonary valve regurgitation following balloon valvuloplasty for moderate to severe pulmonary valve stenosis is a known late outcome of this procedure. OBJECTIVE: The aim of the study was to characterise the status of pulmonary regurgitation on follow up after pulmonary valve balloon dilatation (PVBD), and to study the determinant of the severity of PR. MATERIALS AND METHODS: We retrospectively reviewed 50 consecutive patients, aged 2 days to 18 years, with isolated pulmonary valve stenosis, who had undergone PVBD in 2004-2009 and were assessed with follow-up Doppler echocardiography. The impact of balloon to annulus ratio, age, and valve anatomy on the late development of moderate and severe pulmonary valve regurgitation following balloon valvuloplasty was analysed. RESULTS: Six patients (12%) had no pulmonary valve regurgitation; 32 (64%) had mild, 9 (18%) had moderate, and 3 (6%) had severe pulmonary valve regurgitation at a mean follow-up of 4 years. Balloon to annulus ratio, age, and valve anatomy were not statistically significant predictors for moderate and severe pulmonary valve regurgitation. CONCLUSIONS: The majority of patients in our population had mild pulmonary valve regurgitation. Moderate to severe pulmonary valve regurgitation was well tolerated at midterm follow-up. Age, balloon to annulus ratio, and valve anatomy were not statistically significant predictors for the late development of moderate and severe valve regurgitation. Large and longer follow-up studies are needed to address this question.
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Balushi et al. (2013) conducted a cohort in Isolated pulmonary valve stenosis (n=50). Balloon valvuloplasty was evaluated on Severity of pulmonary valve regurgitation at follow-up. Following balloon valvuloplasty for pulmonary valve stenosis, 88% of patients developed pulmonary valve regurgitation at a mean follow-up of 4 years, with 64% having mild, 18% moderate, and 6% severe regurgitation.
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