Severe pulmonary regurgitation was significantly associated with right ventricle dysfunction detected by strain analysis in patients after balloon pulmonary valvuloplasty (p = 0.01).
What are the predictors of pulmonary regurgitation and right ventricular dysfunction in late follow-up after balloon pulmonary valvuloplasty?
Strain analysis is more sensitive than conventional echocardiography for detecting right ventricular dysfunction related to severe pulmonary regurgitation in the late follow-up of balloon pulmonary valvuloplasty.
Absolute Event Rate: 0% vs 0%
Abstract Objectives: To evaluate the right ventricle function by conventional echocardiographic methods and strain analysis in the long term after balloon pulmonary valvuloplasty. In addition, we investigated the relationship between pulmonary regurgitation, demographic data at the time of the procedure, and right ventricle dysfunction in late follow-up. Methods: The records of patients submitted to balloon pulmonary valvuloplasty from 2001 to 2015 in a single centre were reviewed. From that sample, a revised cohort was formed, and the patients were submitted to clinical and echocardiographic evaluations. Results: The retrospective and the revised cohort analyses included 73 and 18 patients, respectively. In the follow-up, pulmonary regurgitation was observed in all patients, and there was a significant worsening of its magnitude over time ( p < 0.001); the severity of pulmonary regurgitation was associated with balloon pulmonary valvuloplasty performed in patients with weight < 3 kg ( p < 0.03), body surface area < 0.3 m 2 ( p < 0.04), and < 1 year of age ( p < 0.006). Global longitudinal systolic strain of the right ventricle was abnormal in 8 of 18 patients, and conventional methods were abnormal in 2 of 18 patients ( p = 0.001). There was a significant relationship between severe pulmonary regurgitation and right ventricle dysfunction detected only by strain evaluation ( p = 0.01). Conclusions: The severity of pulmonary regurgitation was related to the impairment of right ventricle function detected by strain. The predictors of pulmonary regurgitation severity in late follow-up were age < 1 year, weight < 3 kg, and body surface area < 0.3 m 2 .
Azevedo et al. (Mon,) reported a other. Severe pulmonary regurgitation was significantly associated with right ventricle dysfunction detected by strain analysis in patients after balloon pulmonary valvuloplasty (p = 0.01).