Key result
Preprocedural CTA findings of RVOT landing zone distance ≤3 mm to a coronary artery (P<0.001) and ≤8 mm to the chest wall (P=0.026) were significantly associated with increased coronary compression risk during TPVR.
Why the study?
Coronary compression is a serious complication of transcatheter pulmonary valve replacement, but the value of preprocedural CT angiography to assess this risk remains largely unexplored.
Does preprocedural CTA predict the risk of coronary compression in patients with congenital heart disease undergoing TPVR?
Cohort (n=66)
Does preprocedural CTA predict the risk of coronary compression in patients with congenital heart disease undergoing TPVR?
p-value: p=<0.001
Preprocedural CTA can identify patients at high risk for coronary compression during TPVR by measuring RVOT distances to coronary arteries and the chest wall.
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CTA distances may flag TPVR compression risk; leaves open prospective validation before guiding practice.
Rinaldi et al. (2020) conducted a cohort in Congenital heart disease undergoing transcatheter pulmonary valve replacement (n=66). RVOT to coronary artery distance ≤3 mm and RVOT to chest wall distance ≤8 mm on CTA vs. Distance >3 mm to coronary artery and >8 mm to chest wall was evaluated on Coronary compression (p=<0.001). Preprocedural CTA findings of RVOT landing zone distance ≤3 mm to a coronary artery (P<0.001) and ≤8 mm to the chest wall (P=0.026) were significantly associated with increased coronary compression risk during TPVR.
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