October 1, 1998Journal of Cardiovascular Electrophysiology
New Evidence that AV Node Slow Pathway Conduction Directly Influences Fast Pathway Function
Why the study?
Does successful slow pathway ablation reduce the fast pathway effective refractory period in patients with typical AV nodal reentrant tachycardia?
Population
26 consecutive patients with typical AV nodal reentrant tachycardia who underwent slow pathway ablation.
Comparison
Successful slow pathway ablation. vs Baseline and unsuccessful ablation attempts.
Design
Cohort
Authors
Discussion
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Member takes
Implication
Suggests loss of electrotonic effects on fast pathway after successful ablation; supports mechanistic understanding of AVNRT but leaves clinical impact open.
Structured PICO
Does successful slow pathway ablation reduce the fast pathway effective refractory period in patients with typical AV nodal reentrant tachycardia?
P
Population
26 consecutive patients with typical AV nodal reentrant tachycardia (mean age 45 +/- 3 years, 20 women and 6 men) who underwent slow pathway ablation.
I
Intervention
Successful slow pathway ablation (defined as complete elimination of dual AV node physiology).
C
Comparator
Baseline (prior to ablation) and unsuccessful ablation attempts.
O
Outcome
Fast pathway effective refractory period (ERP) at a drive train cycle length of 600 msec.surrogate
Shortening of the fast pathway effective refractory period following slow pathway ablation is likely due to the elimination of a direct effect of slow pathway conduction on fast pathway function.
Cite This Study
Geller et al. (1998) studied this question.