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de novo HCC is also seen in children. 1 Hemangioendothelioma presents as massive hepatomegaly with severe anemia and cardiac failure. In addition, there may be features of hypothyroidism (constipation and lethargy). There is a high expression of type III iodothyronine deiodinase activity within the tumor. This enzyme is responsible for the conversion of T4 and T3 to inactive metabolites. Sudden onset of pain in the right upper quadrant and recurring ascites with prominent dilated abdominal veins can be seen in acute BCS.
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Sarma et al. (2024) studied this question.
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