Why the study?
Does multiagent chemotherapy improve survival in children with newly diagnosed stage IV metastatic neuroblastoma?
Population
104 eligible children with newly diagnosed stage IV neuroblastoma entered on two clinical studies by the…
Design
Cohort
Authors
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Supports multiagent chemotherapy responses in pediatric metastatic neuroblastoma; leaves open randomized confirmation of survival benefit.
Does multiagent chemotherapy improve survival in children with newly diagnosed stage IV metastatic neuroblastoma?
Multiagent chemotherapy resulted in complete or partial response in the majority of children with metastatic neuroblastoma, with improved long-term survival compared to previous studies, particularly in children <1 year or >6 years of age.
Finklestein et al. (1979) studied this question.
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