Why the study?
Does the toxicity profile differ between citalopram, venlafaxine, mirtazapine, and nefazodone after overdose?
Does the toxicity profile differ between citalopram, venlafaxine, mirtazapine, and nefazodone after overdose?
In overdose, mirtazapine and nefazodone appear relatively safe, whereas citalopram and venlafaxine carry higher risks of seizures, ICU admission, and specific cardiovascular or neurological toxicities.
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May inform agent-specific monitoring in antidepressant overdose; leaves open comparative safety implications for practice.
Kelly et al. (2004) studied this question.
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