Key result
This review summarizes the pharmacological, experimental, and clinical evidence regarding the use of ranolazine for the prevention and management of various cardiac arrhythmias.
Why the study?
Does ranolazine prevent or manage cardiac arrhythmias?
Does ranolazine prevent or manage cardiac arrhythmias?
This review highlights the emerging evidence for ranolazine's utility beyond refractory angina, specifically in the management of atrial and ventricular arrhythmias.
Ranolazine may aid arrhythmia management beyond angina; hypothesis-generating review leaves open need for dedicated RCTs.
Ranolazine utilization in the management of refractory angina has been established by multiple randomized clinical studies. However, there is growing evidence showing an evolving role in the field of cardiac arrhythmias. Multiple experimental and clinical studies have evaluated the role of ranolazine in prevention and management of atrial fibrillation, with ongoing studies on its role in ventricular arrhythmias. In this review, we will discuss the pharmacological, experimental, and clinical evidence behind ranolazine use in the management of various cardiac arrhythmias.
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Saad et al. (2015) conducted a review in Cardiac arrhythmias. Ranolazine was evaluated. This review summarizes the pharmacological, experimental, and clinical evidence regarding the use of ranolazine for the prevention and management of various cardiac arrhythmias.
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