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January 1, 2006DiabetesOpen Access

Leucine Regulation of Glucokinase and ATP Synthase Sensitizes Glucose-Induced Insulin Secretion in Pancreatic β-Cells

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Authors

JYJichun YangPeking UniversityRWRyan WongWestern UniversityMPMieJung Park

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Yang et al. (2006) studied this question.

synapsesocial.com/papers/6a7c72bf5d6f11e376eade4dhttps://doi.org/10.2337/diabetes.55.01.06.db05-0938
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Also Consider

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  1. 1Leucine Culture Reveals That ATP Synthase Functions as a Fuel Sensor in Pancreatic β-Cells2004 · 35 citations
  2. 2Regulation of Pancreatic β-Cell Glucokinase2002 · 346 citations
  3. 3Allosteric Activators of Glucokinase: Potential Role in Diabetes Therapy2003 · 539 citations
  4. 4Prolonged exposure of human beta cells to elevated glucose levels results in sustained cellular activation leading to a loss of glucose regulation.1996 · 173 citations
  5. 5The Changes in Adenine Nucleotides Measured in Glucose-stimulated Rodent Islets Occur in β Cells but Not in α Cells and Are Also Observed in Human Islets1998 · 159 citations