Why the study?
Does excessive anticoagulation increase mortality in hospitalized patients with anticoagulant-related major hemorrhage?
Population
101 consecutive inpatients admitted to Brigham and Women's Hospital with major bleeding occurring during…
Comparison
Excessive anticoagulation vs Nonexcessive anticoagulation
Design
Cohort
Follow-up
60 days
Authors
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Should not yet change reversal practices; hypothesis-generating for whether correcting excessive anticoagulation improves survival.
Does excessive anticoagulation increase mortality in hospitalized patients with anticoagulant-related major hemorrhage?
In patients hospitalized with anticoagulant-associated major hemorrhage, excessive anticoagulation independently predicts higher 60-day mortality and 30-day morbidity.
Koo et al. (2004) studied this question.
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