Key result
Advanced imaging techniques, particularly Dynamic Contrast Enhanced (DCE) MRI, have the potential to improve objective assessment of inflammation, patient stratification, and phenotyping in rheumatoid arthritis.
Why the study?
To discuss the potential of advanced imaging, particularly DCE-MRI, for objective assessment of inflammation, monitoring, and patient stratification in rheumatoid arthritis.
DCE-MRI may facilitate enhanced stratification, phenotyping, and objective assessment of inflammation in patients with rheumatoid arthritis.
This is the authors' abstract. We don't add key points for this paper.
In this commentary, we discuss the potential of advanced imaging, particularly Dynamic Contrast Enhanced (DCE) magnetic resonance imaging (MRI) for the objective assessment of the inflammatory process in rheumatoid arthritis (RA). We emphasise the potential of DCE-MRI in advancing the field and exploring new areas of research and development in RA. We hypothesize that different grades of bone marrow edema (BME) and synovitis in RA can be examined and monitored in a more sensitive manner with DCE-MRI. Future treatments for RA may benefit from the application of enhanced imaging of BMEs and synovitis. DCE-MRI may also facilitate enhanced stratification and phenotyping of patients enrolled in clinical trials.
Answers are grounded in this paper and cite their sources.
Hypothesis-generating for DCE-MRI in RA phenotyping; prospective trials needed before clinical adoption.
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Mobasheri et al. (2020) conducted a review in Rheumatoid arthritis. Dynamic Contrast Enhanced (DCE) MRI was evaluated. Advanced imaging techniques, particularly Dynamic Contrast Enhanced (DCE) MRI, have the potential to improve objective assessment of inflammation, patient stratification, and phenotyping in rheumatoid arthritis.
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