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November 1, 20148 citationsOpen Access

Detection of human bocavirus in children with acute respiratory tract infections in Lanzhou and Nanjing, China.

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Population

2,175 children <173 months of age with acute respiratory tract infections from two hospitals in Lanzhou and…

Design

Cross-sectional

Key result

HBoV1 was detected in 10.8% of children with acute respiratory tract infections, with 72.3% of positive cases co-infected with other respiratory viruses.

Authors

JWJianjun WuJYJin YuNLNa Lin

Discussion

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Overview

HBoV1 detection in pediatric ARTI should not change management; leaves open its independent role amid frequent co-infections.

Study Design

Type

Observational (n=2,175)

Multicenter

Yes

Structured PICO

P
Population
2,175 children under 15 years of age with acute respiratory tract infections evaluated for human bocavirus 1 prevalence and co-infections in two Chinese hospitals.
O
Outcome
Prevalence of HBoV1 and its co-infection with other respiratory viruses

HBoV1 is prevalent in children with acute respiratory tract infections in China and frequently co-occurs with other respiratory viruses, particularly in colder seasons.

Limitations

  • Potential sample selection bias due to some patients or legal guardians declining to participate.
  • Samples of excluded cases were not collected, limiting the understanding of infection frequency in those populations.
  • Lack of a control group of children without respiratory tract infections to explore the relationship between HBoV1 in health and disease.
  • Potential sample selection bias due to missed cases from lack of consent
  • Lack of a healthy control group (children without respiratory tract infections) to compare HBoV1 prevalence

Cite This Study

Wu et al. (2014) conducted an observational in Acute respiratory tract infections (n=2,175). Human bocavirus 1 (HBoV1) vs. HBoV1-negative was evaluated on HBoV1 detection rate. HBoV1 was detected in 10.8% of children with acute respiratory tract infections, with 72.3% of positive cases co-infected with other respiratory viruses.

synapsesocial.com/papers/6a7c8167d19ead88658f146fhttps://doi.org/10.3967/bes2014.110
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