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February 25, 2025Microbiology SpectrumOpen Access

Human bocavirus-1 infection in hospitalized pediatric patients with acute respiratory tract infections

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Why the study?

There is a poor understanding of the characteristics and clinical manifestations of human bocavirus-1 (HBoV1) infection, and few studies have thoroughly analyzed co-infecting pathogens and their patterns in pediatric acute respiratory tract infections.

Population

5,021 hospitalized pediatric patients with respiratory infections in the Guangxi region

Design

Cohort study

Key result

Among 5,021 hospitalized children with respiratory infections, HBoV1 was detected in 8.48%, with 96% of these cases involving co-infections with other pathogens.

Authors

JTJie TanZHZiyin HuangWTWenting Tang

Discussion

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Member takes

Overview

May support multiplex testing in pediatric ARTIs; hypothesis-generating and requires prospective validation before practice change.

Study Design

Type

Cohort (n=5,021)

Structured PICO

P
Population
5,021 hospitalized pediatric patients with acute respiratory tract infections analyzed for HBoV1 and co-existing respiratory pathogens.
O
Outcome
Infection status, clinical characteristics, and co-infection patterns of HBoV1

HBoV1 infection is present in 8.48% of hospitalized children with acute respiratory tract infections, with a very high rate (96%) of co-infection with other pathogens.

Cite This Study

Tan et al. (2025) conducted a cohort in Acute respiratory tract infections (n=5,021). Human bocavirus-1 (HBoV1) infection was evaluated on Detection rate of HBoV1. Among 5,021 hospitalized children with respiratory infections, HBoV1 was detected in 8.48%, with 96% of these cases involving co-infections with other pathogens.

synapsesocial.com/papers/6a4af276f6034ba310a87164https://doi.org/10.1128/spectrum.02985-24
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