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May 29, 2009Science

Topographical and Temporal Diversity of the Human Skin Microbiome

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Authors

EGElizabeth A. GriceUniversity of PennsylvaniaHKHeidi H. KongNational Institutes of HealthSCSean ConlanNational Human Genome Research Institute

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Implication

Genomic survey reveals site-specific diversity and temporal stability across healthy human skin, providing a baseline for investigating cutaneous microbiome dynamics in health and disease.

Key Points

  • To characterize the spatial and temporal variation of bacterial communities across diverse anatomical microenvironments on healthy human skin.
  • Analyzed 16S ribosomal RNA gene sequences collected from 20 distinct skin sites in healthy humans.
  • Evaluated bacterial community composition, diversity, and temporal stability across varying physiological skin environments.
  • Physiologically comparable skin sites harbor similar bacterial communities.
  • Microbial community complexity and stability depend directly on the specific physiological characteristics of the anatomical skin site.

Cite This Study

Grice et al. (2009) studied this question.

synapsesocial.com/papers/6a7c863d5330a2aba4e42720https://doi.org/10.1126/science.1171700
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