Why the study?
Does total knee arthroplasty compared to total hip arthroplasty increase the risk of deep venous thrombosis in patients without prophylactic anticoagulation?
Does total knee arthroplasty compared to total hip arthroplasty increase the risk of deep venous thrombosis in patients without prophylactic anticoagulation?
In Japanese patients not receiving prophylactic anticoagulation, total knee arthroplasty carries a 3.2-fold higher risk of deep venous thrombosis compared to total hip arthroplasty.
TKA without anticoagulation was associated with higher DVT risk than THA; leaves open procedure-specific prophylaxis trials.
A single center, prospective, epidemiologic study was conducted to estimate the incidence of deep venous thrombosis detected by venography in patients in Japan undergoing total hip arthroplasty or total knee arthroplasty without prophylactic anticoagulant therapy. Venograms of 164 patients who had total hip arthroplasty and 138 patients who had total knee arthroplasty were evaluated. The incidences of deep venous thrombosis were 22.6% in patients who had total hip arthroplasty and 48.6% in those who had total knee arthroplasty. The incidences of proximal deep venous thrombosis were 9.8% in patients who had total hip arthroplasty and 14.5% in those who had total knee arthroplasty. Statistical analysis revealed that the type of operation influenced the development of deep venous thrombosis. Patients who had total knee arthroplasty were 3.2 times more likely to have deep venous thrombosis develop than were patients who had total hip arthroplasty. Body mass index and age were identified as statistically significant risk factors.
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Fujita et al. (2000) studied this question.
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