Cardioprotective effects of carvacrol in the isoproterenol-induced myocardial infarction model

Figures

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  Fig. 1. Weight changes over the weeks in experimental groups

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  Fig. 2. Evaluation of systolic blood pressures before and after the treatment is shown in the graphs. Data are represented as mean ± standard deviation. * < 0.05 ** < 0.01

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  Fig. 3. Evaluation of diastolic blood pressures before and after the treatment is shown in the graphs. Data are represented as mean ± standard deviation. ** < 0.01

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  Fig. 4. Evaluation of mean arterial pressures before and after the treatment is shown in the graphs. Data are represented as mean ± standard deviation. * < 0.05

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  Fig. 5. Evaluation of heart rate values before and after the treatment is shown in the graphs. Data are represented as mean ± standard deviation. * < 0.05 ** < 0.01

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  Fig. 6. Evaluation of serum troponin T between groups. Data are represented as mean ± standard deviation. * < 0.05 ** < 0.01 *** < 0.001

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  Fig. 7. Evaluation of serum BNP between groups. Data are represented as mean ± standard deviation. *** < 0.001

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  Fig. 8. Evaluation of heart IL-6 levels between groups. Data are represented as mean ± standard deviation. * < 0.05 ** < 0.01 *** < 0.001

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  Fig. 9. Evaluation of heart GDF-15 levels between groups. Data are represented as mean ± standard deviation. * < 0.05 ** < 0.01 *** < 0.001

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  Fig. 10. Light microscopic findings in the rat heart tissue. a: Control group; Blue arrows: Healthy discus intercalaris, Red star: Centrally located and oval shaped cell nuclei. b, c: MI groups. Yellow star: Mononuclear cell infiltration. Red arrows: Necrotic myocardial cell. İron- Hematoksilen (Nikon Eclipse Si, Tokyo, Japan, X20 and X40)

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  Fig. 11. Light microscopic findings in the rat heart tissue. d: MI group. Yellow arrows: Edema, e: MI + CAR group and f: CAR group. İron Hemotoksilen (Nikon Eclipse Si, Tokyo, Japan, X20 and X40)

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  Fig. 12. Histopathological findings of rat heart tissue. Graph exhibiting necrosis, edema, and mononuclear cell infiltration in experimental groups. Data were presented as mean ± standard deviation and median (min-max).; p < 0.05, *; p < 0.01, *; p < 0.001