Key result
The assessment of aortic stenosis is expected to transition from relying heavily on echocardiographic gradients to active surveillance with multimodality imaging, serum biomarkers, and genetic assessment.
The assessment of aortic stenosis is transitioning from relying solely on echocardiographic gradients to incorporating multimodality imaging, serum biomarkers, and genetic assessment.
Highlights a conceptual shift toward personalized aortic stenosis surveillance; leaves open how these novel multimodality and.
Calcific aortic stenosis (AS) is one of the most common acquired valvular heart diseases in industrialized nations. It is a slowly progressive disease and with the aging population, the prevalence of AS is expected to increase. Doppler echocardiography is used to classify patients based on severity of stenosis. Research efforts on how to better identify and risk-assess these patients are currently underway using advanced imaging modalities and serum biomarkers. Thus far, medications for AS prevention have been unsuccessful. As technology progresses, the assessment of AS will transition from one heavily weighed on echocardiographic gradients to one of active surveillances with multimodality imaging, serum biomarkers and genetic assessment.
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Safi et al. (2017) conducted a review in Calcific aortic stenosis. The assessment of aortic stenosis is expected to transition from relying heavily on echocardiographic gradients to active surveillance with multimodality imaging, serum biomarkers, and genetic assessment.
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