Key result
Lifestyle and constitutional factors explain ~24% of plasma fibrinogen variance in men.
Cross-Sectional (n=711)
No
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Dietary, social, and constitutional determinants of plasma concentrations of some major risk factors for ischaemic heart disease were investigated in a cross sectional study among 711 men from the general population aged 30-69. For high density lipoprotein cholesterol (HDL-C) six variables were significantly associated with plasma concentrations, and these variables explained 12.6% of the variance. For low density lipoprotein cholesterol (LDL-C), total cholesterol (T-C), and triglyceride 8.4%, 7.5%, and 18.5% of the variance was explained by significantly associated variables. Fibrinogen concentrations determined chemically were significantly associated with age, smoking habit, body mass index, alcohol consumption, and intake of cereal fibre (24.2% variance). These data provide some encouragement for the possibility of dietary intervention to influence plasma concentrations of major risk factors for ischaemic heart disease in men.
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Yarnell et al. (1983) conducted a cross-sectional in Ischaemic heart disease risk factors (n=711). Dietary, social, and constitutional determinants (including age, smoking, BMI, alcohol, and cereal fibre) was evaluated on Variance in plasma concentrations of lipoproteins (HDL-C, LDL-C, total cholesterol, triglyceride) and fibrinogen. Dietary, social, and constitutional factors explained 24.2% of plasma fibrinogen variance and 7.5%-18.5% of plasma lipoprotein variance in men.
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