Key result
ACE I/D and ACE G2350A gene polymorphisms showed no statistically significant differences in genotype or allele frequencies between essential hypertension patients, elite athletes, and healthy controls.
Why the study?
ACE gene I/D and G2350A polymorphisms regulate cardiovascular mechanisms through the renin-angiotensin system and affect physical performance important for athletes.
Case-Control (n=79)
No
Answers are grounded in this paper and cite their sources.
Objective: Angiotensin-converting enzyme (ACE) gene produces an ACE protein which is the key component of the renin-angiotensin system and contains several polymorphisms which affects the physical performance that is significantly important for athletes. Insertion/deletion (I/D) and G2350A polymorphisms which have one of the most powerful influences in the ACE gene is known to regulate cardiovascular mechanisms by taking a role in angiotensin-system.
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Tuba Günel (2020) conducted a case-control in Essential hypertension and sports performance (n=79). ACE I/D and ACE G2350A gene polymorphisms vs. Healthy controls was evaluated on Genotype and allele frequencies of ACE I/D and ACE G2350A polymorphisms. ACE I/D and ACE G2350A gene polymorphisms showed no statistically significant differences in genotype or allele frequencies between essential hypertension patients, elite athletes, and healthy controls.
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