Key result
Angiotensin I converting enzyme gene insertion/deletion polymorphism is discussed in relation to its effects on human physical performance.
Why the study?
Does the ACE gene I/D polymorphism influence human physical performance and trainability?
Does the ACE gene I/D polymorphism influence human physical performance and trainability?
Answers are grounded in this paper and cite their sources.
The ACE gene I/D polymorphism is a genetic factor that influences human physical performance, with the I/I genotype associated with endurance and the D/D genotype with power.
Angiotensin I converting enzyme (ACE) gene Insertion/Deletion (I/D) polymorphism was first shown as a genetic factor which influences human physical performance in 1998. Since then, various gene polymorphisms which influence physical performance and trainability have been reported. ACE is a key enzyme which produces angiotensin II in the renin-angiotensin system, and its activity was determined by I/D polymorphism. Many studies indicate that the I/I genotype is frequently found in elite endurance athletes, while the D/D genotype is frequently found in power-oriented elite athletes. Longitudinal studies show that the D/D genotype may contribute to enhanced strength trainability. However, it is still unclear whether the I/I genotype enhances endurance trainability. Therefore, the ACE gene I/D polymorphism can be a genetic factor which influences human physical performance.
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Tobina et al. (2008) conducted a review in Physical performance. Angiotensin I converting enzyme (ACE) gene insertion/deletion polymorphism was evaluated. Angiotensin I converting enzyme gene insertion/deletion polymorphism is discussed in relation to its effects on human physical performance.
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