Why the study?
Does the ACE gene I/D polymorphism influence the therapeutic response to ACE inhibitors in patients with cardiovascular conditions?
Population
Subjects with the angiotensin I-converting enzyme gene insertion/deletion polymorphism, including patients…
Design
Review
Authors
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May guide personalized ACE inhibitor selection; leaves open prospective validation before clinical adoption.
Does the ACE gene I/D polymorphism influence the therapeutic response to ACE inhibitors in patients with cardiovascular conditions?
The ACE gene I/D polymorphism may modulate individual responses to ACE inhibitors, highlighting a potential pharmacogenomic approach to cardiovascular therapy that requires further validation.
Bruno Baudin (2000) studied this question.
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