Why the study?
Does ACE gene I/D polymorphism affect the Renin-angiotensin system and blood pressure response during a single bout of exercise in young men?
Population
12 young men (6 insertion homozygous (I/I) and 6 deletion homozygous (D/D) for the ACE gene)
Comparison
Multi-load exercise test at 1/2 lactate… vs Comparison between I/I and D/D genotypes
Design
Cross-sectional
Follow-up
3 minutes after finishing exercise
Authors
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ACE I/D polymorphism does not alter acute exercise BP or Ang II responses despite lower ACE activity in I/I; leaves open effects on training adaptations.
Does ACE gene I/D polymorphism affect the Renin-angiotensin system and blood pressure response during a single bout of exercise in young men?
The ACE gene I/D polymorphism affects plasma ACE activity but is not associated with differences in plasma Angiotensin II concentration or blood pressure during a single session of exercise.
Tobina et al. (2006) studied this question.
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