Key result
Dysregulated intracellular nucleic acid sensing causes rare human autoimmune diseases, providing an evolutionary framework for understanding more common autoimmune disorders.
Design
Review
Authors
Loading...
Provides a conceptual framework for understanding autoimmune pathogenesis; leaves open whether targeting these nucleic acid sensing pathways can yield.
This review provides a conceptual framework for understanding how dysregulated intracellular nucleic acid sensing contributes to the pathogenesis of autoimmune diseases.
Crowl et al. (2017) conducted a review in Autoimmunity and rare human diseases caused by dysregulated nucleic acid sensing. Dysregulated intracellular nucleic acid sensing causes rare human autoimmune diseases, providing an evolutionary framework for understanding more common autoimmune disorders.
Synapse has enriched 2 closely related papers on similar clinical questions. Consider them for comparative context: