Key result
Athletic training was associated with a significantly greater maximal forearm skin blood flow response to acetylcholine after acute exercise compared to sedentary status (987% vs 638%; p=0.001).
Why the study?
Does acute incremental exercise improve endothelium-dependent forearm skin blood flow in trained versus sedentary healthy young males?
Case-Control (n=49)
Does acute incremental exercise improve endothelium-dependent forearm skin blood flow in trained versus sedentary healthy young males?
Acute exercise enhances endothelium-dependent vasodilation, with a significantly greater magnitude of improvement observed in trained compared to sedentary young males.
Answers are grounded in this paper and cite their sources.
Greater endothelial response to acute exercise in trained adolescents; hypothesis-generating for training effects on vascular reactivity.
Aim: to investigate vascular reactivity on forearm skin blood flow (FSBF) in response to iontophoresis of acetylcholine (ACh) after an acute exercise. Materials and method: 49 healthy male subjects 29 trained and 20 sedentary (recruited according to their oxygen consumption) participated in this case control study (mean age: 15 ± 1 year). Incremental exercise testing was performed by means of an individualized and personalized exercise test protocol. FSBF was measured before and after exercise using a laser Doppler flowmeter in response to local iontophoresis of a cumulative dose of ACh. Results: Although groups were not different in age, height or body mass index, weight, resting heart rate, maximum oxygen consumption was significantly different (sedentary 40.05 ± 4.53 and trained 51.65 ± 5.76 ml.min-1. kg-1) (p<0.05; p<0.001; p<0.001, respectively). The mean response of FSBF to ACh was significantly increased after incremental exercise in the two groups (349%). Maximal FSBF response to ACh was significantly greater in trained (987% ± 78) than in sedentary (638% ± 42) (p=0.001) after a single acute exercise. Conclusion: Response of FSBF to ACh-induced endothelium dependent relaxation was affected by the level of training whether before or after an acute exercise.
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Zguira et al. (2015) conducted a case-control in Healthy (n=49). Athletic training vs. Sedentary status was evaluated on Maximal forearm skin blood flow (FSBF) response to acetylcholine after a single acute exercise (p=0.001). Athletic training was associated with a significantly greater maximal forearm skin blood flow response to acetylcholine after acute exercise compared to sedentary status (987% vs 638%; p=0.001).
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