Key result
Behavioral lifestyle interventions involving calorie restriction with or without physical activity appear to promote weight loss among breast cancer survivors, with unclear cardiometabolic effects.
Why the study?
Up to 90% of females gain weight during and after breast cancer treatment, increasing the risk of recurrence and comorbidities, and behavioral lifestyle interventions may offer nonpharmacological options to decrease weight gain and cardiometabolic risk.
Do behavioral lifestyle interventions focused on diet with or without physical activity improve body weight and cardiometabolic risk markers in breast cancer survivors?
Do behavioral lifestyle interventions focused on diet with or without physical activity improve body weight and cardiometabolic risk markers in breast cancer survivors?
Calorie restriction with or without physical activity promotes weight loss in breast cancer survivors, but more robust studies are needed to determine effects on cardiometabolic risk.
May support weight management in breast cancer survivors; leaves open optimal design and effects on recurrence.
BACKGROUND: In 8 females, 1 will be diagnosed with breast cancer in their lifetime. Although medical advances have increased the likelihood of survival, up to 90% of females will gain weight during and after treatment increasing the risk of breast cancer recurrence and obesity-related comorbidities in survivorship. Behavioral lifestyle interventions focused on diet with or without physical activity can provide breast cancer survivors nonpharmacological options to decrease weight gain and cardiometabolic risk. METHOD: A PubMed search was conducted to identify all behavioral lifestyle interventions focused on diet or diet combined with physical activity longer than 4 weeks of duration in breast cancer survivors that included body weight as an outcome. This review aims to summarize the effects on body weight, body composition, and cardiometabolic risk markers. RESULTS: The review shows there is high heterogeneity in type and duration of the intervention to affect weight and cardiometabolic risk in survivorship. Calorie restriction with and without physical activity appears to promote weight loss among breast cancer survivors. However, the effects on cardiometabolic factors are less clear. CONCLUSIONS: Future studies should be powered for body weight and cardiometabolic effects. Researchers should also consider interventions that (1) are less complex, (2) recruit a more racially and ethnically diverse sample, (3) integrate resistance training, (4) implement the intervention in closer proximity to diagnosis, (5) target weight management in this population before it occurs, and (6) analyze body composition in addition to body weight measurements.
No takes yet. Share an insight, caveat, or question.
Gabel et al. (2024) conducted a review in Breast cancer. Behavioral lifestyle interventions (diet with or without physical activity) was evaluated on Body weight, body composition, and cardiometabolic risk markers. Behavioral lifestyle interventions involving calorie restriction with or without physical activity appear to promote weight loss among breast cancer survivors, with unclear cardiometabolic effects.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: