What question did this study set out to answer?

To identify the clinicopathological characteristics, treatment patterns, and clinical outcomes of pediatric central nervous system tumors managed at a tertiary care center.

January 1, 2017Journal of Pediatric NeurosciencesOpen Access

Profile and outcome of pediatric brain tumors – Experience from a tertiary care pediatric oncology unit in South India

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To identify the clinicopathological characteristics, treatment patterns, and clinical outcomes of pediatric central nervous system tumors managed at a tertiary care center.
Retrospective review of medical records for children aged <18 years (N = 52) diagnosed with central nervous system tumors between January 2012 and November 2016.
Histopathological classification was conducted according to the 2007 WHO guidelines, tracking multidisciplinary modalities including neurosurgery, radiation therapy, and chemotherapy.
Of the 52 children (66.6% male; 50% aged 0–4 years), 59.6% had supratentorial lesions and 48% presented with embryonal tumors, with 73% receiving surgical resection or biopsy.
Overall, 15.3% of patients (n = 8) died from disease progression, while 44% abandoned therapy due to tumor recurrence or progression, predominantly among high-risk subtypes including pontine glioma and medulloblastoma.

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Implication

Retrospective study reports high rates of treatment abandonment in pediatric brain tumor patients, highlighting barriers to multidisciplinary care in resource-limited settings.

Cite This Study

Srinivasan et al. (2017) studied this question.

synapsesocial.com/papers/6a7ca5f84ec837fd6928a4e7 https://doi.org/10.4103/jpn.jpn_31_17

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Implication

Retrospective study reports high rates of treatment abandonment in pediatric brain tumor patients, highlighting barriers to multidisciplinary care in resource-limited settings.

Profile and outcome of pediatric brain tumors – Experience from a tertiary care pediatric oncology unit in South India

Key Points

Discussion

Implication

Cite This Study

Profile and outcome of pediatric brain tumors – Experience from a tertiary care pediatric oncology unit in South India

Key Points

Discussion

Implication

Cite This Study

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