Why the study?
Does epidural diamorphine added to bupivacaine improve analgesia in primigravid women in labour?
Does epidural diamorphine added to bupivacaine improve analgesia in primigravid women in labour?
The addition of epidural diamorphine to bupivacaine significantly improves analgesia and reduces the need for additional bupivacaine in primigravid women in labour.
Supports adding epidural diamorphine to bupivacaine for labor analgesia in primigravidae; extends RCT evidence on opioid adjuvants.
A double-blind randomised study was performed to assess the analgesic effect of epidural diamorphine, administered with bupivacaine, on primigravid women in labour. Fifty patients received 0.25% bupivacaine 10 ml via the epidural catheter as their initial dose; patients in Group 1 received diamorphine 5 mg with the bupivacaine. A 0.1% bupivacaine infusion was started at 10 minutes and bolus doses of bupivacaine were given if required. There was a significant reduction in rate of bupivacaine administration, pain scores at 20 and 30 minutes, number of supplements required, and degree of motor blockade in the diamorphine group.
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McGrady et al. (1989) studied this question.
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