The study provides evidence that Kv1.5 channels bind with alpha-actinin-2, linking them to the actin cytoskeleton and regulating current density in HEK cells.
No takes yet. Share an insight, caveat, or question.
No immediate clinical implications from HEK-cell data; leaves open alpha-actinin-2 regulation of native Kv1.5 in cardiomyocytes.
Maruoka et al. (2000) studied this question.
Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context: