Single crystal zinc oxide nanocombs were synthesized in bulk quantity by vapor phase transport. A glucose biosensor was constructed using these nanocombs as supporting materials for glucose oxidase (GOx) loading. The zinc oxide nanocomb glucose biosensor showed a high sensitivity (15.33μA∕cm2mM) for glucose detection and high affinity of GOx to glucose (the apparent Michaelis-Menten constant KMapp=2.19mM). The detection limit measured was 0.02mM. These results demonstrate that zinc oxide nanostructures have potential applications in biosensors.
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Wang et al. (2006) studied this question.
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