Why the study?
Does inhalation of nitrous oxide induce specific EEG changes in humans?
Population
Human subjects
Comparison
Inhalation of analgesic concentrations of 30%… vs Baseline/control EEG pattern
Design
Other
Follow-up
Approximately 1 hour after cessation
Authors
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34 Hz FOA may mark nitrous oxide effect; leaves open validation as an analgesia monitor in prospective studies.
Does inhalation of nitrous oxide induce specific EEG changes in humans?
Nitrous oxide induces a characteristic 34 Hz fast oscillatory activity on EEG that correlates with concentration and unresponsiveness, which could serve as a clinical monitor for analgesia.
Yamamura et al. (1981) studied this question.
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