September 1, 1998Journal of Applied Physiology

Image-analysis-based assessment of the effects of the “Ca2+-jump” technique on sarcomere uniformity

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Population

skinned rabbit psoas muscle fiber segments (segment lengths typically below 500 micrometer)

Design

Preclinical

Authors

MSMichael SlawnychUniversity of British Columbia LMLillian MorishitaUniversity of British Columbia BBB BresslerUniversity of British Columbia

Discussion

Member takes

Implication

No immediate clinical implications for muscle assessment; hypothesis-generating in animal models and requires human validation.

Structured PICO

Population

skinned rabbit psoas muscle fiber segments (segment lengths typically below 500 micrometer)

Intervention

Ca2+-jump activation protocol (contractions in pCa 4.6 preceded by short-duration preactivation soaks in a solution replacing EGTA with hexamethylenediamine-N, N, N', N'-tetraacetate)

Outcome

maintenance of fiber quality assessed by examining the Fourier spectra of the muscle fiber images before, during, and after activationsurrogate

The Ca2+-jump preactivation protocol improves the maintenance of fiber quality and accelerates tension development in skinned rabbit muscle fibers.

Cite This Study

Slawnych et al. (1998) studied this question.

synapsesocial.com/papers/6a7cb3de4f6c5ab12328a76a https://doi.org/10.1152/jappl.1998.85.3.955

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Image-analysis-based assessment of the effects of the “Ca2+-jump” technique on sarcomere uniformity

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Image-analysis-based assessment of the effects of the “Ca2+-jump” technique on sarcomere uniformity

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider