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The construction of a high-strength hydrogel with integrated functions by photo-initiated copolymerization of temperature-sensitive and hydrogen-bonding monomers is described. The hydrogen-bonding and thermoresponsive surface of hydrogels offers a multifunctional platform, where reverse gene transfection and gene-modified cell detachment can be achieved for the potential use in the regeneration and replacement of soft tissue.
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Tang et al. (2010) studied this question.
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