A 16-year-old black girl presented to the emergency room with increased thirst, frequent urination, fatigue, and an 11-kg weight loss in the preceding two to three weeks.The triad of polydipsia, polyuria, and polyphagia with weight loss is a classic presentation of diabetes mellitus. Among adolescents, type 1 (autoimmune) diabetes mellitus is the most probable diagnosis. With these three symptoms, the differential diagnosis is quite limited, but diabetes insipidus, either nephrogenic or central, should also be considered. Diabetes insipidus is characterized by polydipsia, polyuria, and weight loss, but not polyphagia, and the weight loss is due to a . . .
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Pinhas‐Hamiel et al. (1999) studied this question.
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