Impact of wideband phase-sensitive inversion recovery motion corrected late gadolinium imaging on 3T cardiac magnetic resonance image quality and diagnostic utility in patients with cardiac implantable electronic devices

Q: What is the clinical evidence from this study?

Study design: Observational. Population: Patients with magnetic resonance imaging-conditional cardiac implantable electronic devices (CIEDs) undergoing 3T CMR (n=9). Intervention: 3T cardiac magnetic resonance (CMR) with wideband phase-sensitive inversion recovery (PSIR) motion-corrected (MOCO) late gadolinium enhancement and spoiled gradient-echo (GRE) cine imaging. Primary outcome: Overall diagnostic image quality on wideband PSIR MOCO.

Q: What does this research mean for the field?

Wideband phase-sensitive inversion recovery motion-corrected late gadolinium enhancement at 3T yields diagnostic image quality in 89% of patients with cardiac implantable electronic devices and alters clinical management in 56%. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

doi:10.1016/j.hroo.2025.12.006

December 13, 2025Heart Rhythm O2Open Access

Impact of wideband phase-sensitive inversion recovery motion corrected late gadolinium imaging on 3T cardiac magnetic resonance image quality and diagnostic utility in patients with cardiac implantable electronic devices

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Key result

Wideband PSIR MOCO 3T CMR achieves ~89% diagnostic image quality in patients with CIEDs.

n=9

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Why the study?

Does 3T CMR with wideband phase-sensitive inversion recovery motion-corrected (PSIR MOCO) sequences provide diagnostic image quality and clinical utility in patients with conditional cardiac implantable electronic devices?

Study Design

Type

Observational (n=9)

Multicenter

No

Structured PICO

Does 3T CMR with wideband phase-sensitive inversion recovery motion-corrected (PSIR MOCO) sequences provide diagnostic image quality and clinical utility in patients with conditional cardiac implantable electronic devices?

P

Population

9 patients (ages 44-75, 3 women and 6 men) with MRI-conditional cardiac implantable electronic devices (2 PPMs, 5 ICDs, 2 CRT-Ds) undergoing 3T cardiac magnetic resonance imaging between October 2023 and January 2024.

I

Intervention

3T cardiac magnetic resonance (CMR) (MAGNETOM Vida, Siemens Healthineers) using a wideband phase-sensitive inversion recovery (PSIR) motion-corrected (MOCO) sequence for delayed gadolinium enhancement (echo time 1.45-2.0 ms; repetition time 647-1196 ms; flip angle 12 degrees) and spoiled gradient-echo (GRE) sequence for cine imaging (echo time 1.9-3.1 ms; repetition time 18-40 ms; flip angle 12 degrees), with routine elevation of the left arm when feasible and device interrogation/reprogramming before and after CMR.

O

Outcome

Image quality (assessed by grading artifact burden on a 1-4 scale across the AHA 17-segment model) and diagnostic utility (defined as change in primary diagnosis, additional qualitative/quantitative information augmenting diagnostic certainty, confirmation of an uncertain pre-CMR diagnosis, or change in clinical management).surrogate

Limitations

Limited case series of 9 patients limits the ability for direct comparisons
Larger studies are needed to explore the relationship between CMR findings and patient outcomes and to compare utilization and image quality differences at 3T and 1.5T
Not broadly representative of all patients with CIEDs given that the case series is predominantly left-sided (8 of 9) and lacks subcutaneous ICDs
Not broadly representative of all patients with CIEDs as the cohort is predominantly left-sided (8 of 9) and lacks subcutaneous ICDs

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Implication

3T CMR using wideband PSIR MOCO and GRE cine sequences is feasible and safe in patients with MRI-conditional CIEDs, providing diagnostic image quality in 89% of cases and altering clinical management in 56%.

Abstract

Cardiac magnetic resonance (CMR) imaging provides a comprehensive quantitative assessment of cardiac function, morphology, and tissue characterization. Higher field strength at 3T offers enhanced signal-to-noise ratio, which enables higher spatial resolution,1 thus enhancing myocardial perfusion imaging, delayed enhancement imaging, and parametric mapping. Increased spatial resolution for late gadolinium enhancement (LGE) enables more precise tissue characterization with important clinical impact, such as providing more optimal procedural planning before ventricular tachycardia (VT) ablation.

Discussion

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Cite This Study

A 2025 study conducted an observational in Patients with magnetic resonance imaging-conditional cardiac implantable electronic devices (CIEDs) undergoing 3T CMR (n=9). 3T cardiac magnetic resonance (CMR) with wideband phase-sensitive inversion recovery (PSIR) motion-corrected (MOCO) late gadolinium enhancement and spoiled gradient-echo (GRE) cine imaging was evaluated on Overall diagnostic image quality on wideband PSIR MOCO. Wideband PSIR MOCO at 3T CMR yielded overall diagnostic image quality in 89% (8 of 9) of patients with conditional CIEDs and led to a change in clinical management in 56% (5 of 9).

synapsesocial.com/papers/6a7cb9b574c8907ce7a8b64b https://doi.org/10.1016/j.hroo.2025.12.006

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Impact of wideband phase-sensitive inversion recovery motion corrected late gadolinium imaging on 3T cardiac magnetic resonance image quality and diagnostic utility in patients with cardiac implantable electronic devices

Figures

Study Design

Structured PICO

Limitations

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

Impact of wideband phase-sensitive inversion recovery motion corrected late gadolinium imaging on 3T cardiac magnetic resonance image quality and diagnostic utility in patients with cardiac implantable electronic devices

Figures

Study Design

Structured PICO

Limitations

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

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