Why the study?
Vascular aging increases cardiovascular disease risk and premature death, driven by increased arterial stiffness index, prompting evaluation of the Lyfas smartphone-based instrument to assess arterial stiffness via arterial photoplethysmography.
Does the Lyfas smartphone application correlate cardiovascular biomarkers with arterial stiffness index in adult smokers, hypertensives, and diabetics?
Does the Lyfas smartphone application correlate cardiovascular biomarkers with arterial stiffness index in adult smokers, hypertensives, and diabetics?
The Lyfas smartphone application demonstrates robust measurement of cardiovascular biomarkers and arterial stiffness index, showing significant correlations with vascular risk factors like smoking and hypertension.
Lyfas smartphone APPG may enable accessible vascular aging screening; leaves open validation and clinical utility.
Background: Vascular aging (VA) increases the risk of Cardiovascular Disease (CVD) and premature deaths. Increased VA is attributed to the extent of the Arterial stiffness index (ASI), which is evident in smokers, diabetics, hypertensives, etc. The authors of this paper have discussed the usage of a smartphonebased healthcare instrument, called Lyfas that works with the principle of arterial photoplethysmography (APPG) and estimates the Pulse rate variability (PRV), which surrogates for the Heart rate variability (HRV) and its correlated digital cardiovascular biomarkers (CVb). PRV reflects cardiovascular autonomic modulation, which helps obtain the ASI by Lyfas.
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Das et al. (2022) studied this question.
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