Why the study?
Does elevated hsCRP or Lp(a) predict cardiovascular events in patients receiving emergency PCI following AMI?
Does elevated hsCRP or Lp(a) predict cardiovascular events in patients receiving emergency PCI following AMI?
Elevated hsCRP, but not Lp(a), serves as a significant prognostic factor for cardiovascular events in patients undergoing emergency PCI for AMI.
Elevated hsCRP was associated with higher post-PCI events in AMI; leaves open incremental prognostic value beyond standard models.
Prognostic Value of High-Sensitivity C-Reactive Protein and Lipoprotein (a) in Acute Myocardial Infarction Patients Receiving Emergency Percutaneous Coronary Intervention In order to study the prognostic value of high-sensitivity C-reactive protein (hsCRP) and lipoprotein (a) [Lp(a)] in patients receiving emergency percutaneous coronary intervention (PCI) following acute myocardial infarction (AMI), we retrospectively reviewed 118 patients who received emergency PCI following AMI from January 2007 to April 2010. The plasma levels of hsCRP and Lp(a) were determined. The incidence of cardiovascular events was compared between patients with an elevated hsCRP level and those with a normal hsCRP level and between patients with an elevated Lp(a) level and those with a normal Lp(a) level. Results showed that the incidence of cardiovascular events was 52.9% in the hsCRP-elevated group and 18.2% in the hsCRP-normal group displaying a significant difference (P=0.011). However, the incidence of cardiovascular events was 35.3% in the Lp(a)-elevated group and 46.4% in the Lp(a)-normal group and statistical analysis revealed no significant difference (P=0.733). HsCRP, but not Lp(a), can serve as a prognostic factor for patients receiving emergency PCI following AMI.
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Ding et al. (2011) studied this question.
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