A 62-year-old right-handed white woman presented with periodic motion-related nausea and vertigo. On physical examination, she had only mild high-frequency hearing loss on the right side. Cranial magnetic resonance imaging (MRI) revealed an unresectable contrast-enhancing lesion measuring 3.6 cm in maximal horizontal diameter within the genu of the corpus callosum, with surrounding abnormal T2/fluid-attenuated inversion recovery (FLAIR) hyperintensity. Stereotactic biopsy of the contrast-enhancing lesion established the diagnosis of glioblastoma (GBM), WHO grade 4.
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Batchelor et al. (2011) studied this question.
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