Why the study?
Do early clinical factors such as admission systolic blood pressure and 24-hour NIHSS predict 3-month survival and functional outcomes in patients with posterior circulation large vessel occlusion after successful mechanical thrombectomy?
Cohort
Do early clinical factors such as admission systolic blood pressure and 24-hour NIHSS predict 3-month survival and functional outcomes in patients with posterior circulation large vessel occlusion after successful mechanical thrombectomy?
Early clinical factors, particularly 24-hour NIHSS, admission systolic blood pressure, and age, are important predictors of 3-month mortality and functional recovery in patients with posterior circulation stroke following successful mechanical thrombectomy.
To investigate the predictive value of clinical factors, including admission systolic blood pressure (SBP), on outcomes in patients with posterior circulation large vessel occlusion (PC-LVO) who underwent successful mechanical thrombectomy (MT), this study retrospectively enrolled patients with PC-LVO who achieved successful recanalization between January 2019 and December 2022, and assessed their 3-month survival and functional outcomes. Using univariable and multivariable logistic regression, model-fitting analyses, and receiver operating characteristic (ROC) curves, it was found that the NIH Stroke Scale score at 24 hours postprocedure (NIHSS24h) independently predicted both poor functional outcomes and mortality in recanalized PC-LVO patients. Admission SBP and age were also significantly associated with prognosis. The results indicate that early vital signs may provide important insights into the risk of poor prognosis or death after MT in PC-LVO patients. These findings offer guidance for prognostic evaluation and patient selection for mechanical thrombectomy in posterior circulation stroke.
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Zhao et al. (2025) conducted a cohort in Posterior circulation large vessel occlusion (PC-LVO). Clinical factors including admission systolic blood pressure, NIHSS at 24 hours, and age was evaluated on 3-month survival and functional outcomes.
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