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March 20, 2008European Heart JournalOpen Access

Age- and gender-specific mortality rates in childhood hypertrophic cardiomyopathy

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Population

150 children with hypertrophic cardiomyopathy, including those presenting with sudden death, 59% male, 39%…

Design

Cohort

Authors

GWGöran WettrellBKB KeetonDHDaniel Holmgren

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Overview

Peak sudden death risk in pre-adolescent HCM may inform earlier monitoring; leaves open guideline revision without prospective data.

Structured PICO

P
Population
150 children with hypertrophic cardiomyopathy (HCM), including those presenting with sudden death, 59% male, 39% familial HCM, from six regional centres of paediatric cardiology.
C
Comparator
Mortality rates from the Swedish National Cause of Death Registry
O
Outcome
Age- and gender-specific mortality (sudden death)hard clinical

Sudden death mortality in childhood HCM peaks between 9 and 13.9 years of age, challenging current guidelines that suggest screening after 12-15 years.

Cite This Study

Wettrell et al. (2008) studied this question.

synapsesocial.com/papers/6a7cc49fa42cae215d7cd7b5https://doi.org/10.1093/eurheartj/ehn122
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