Separation of serum by electrophoresis has shown that certain lipids, found in blood, have the same electrophoretic mobilities as some of the proteins. It is believed that this is due to the attachment of the lipids to the serum proteins in transport by the blood stream. Vitamin A alcohol was found to be carried by acl-globulin (Garbers, Gilhman & Peisach, 1958, 1960); carotene was located mainly with f-globulin, but also with albumin and the a-globulins inhuman serum (Crook & El-Marsafy, 1954) and with albumin in bovine serum (Erwin, Varnell & Page, 1959); cortico- steroids appeared to be associated with albumin (Daughady, 1956 The transport of vitamin D by human serum has been studied (Morgan, Thomas, Haddock & Howard, 1958; Thomas et al. 1959). These authors separated, by electrophoresis on starch, the serum proteins from patients given high doses of vitamin D, and tested the protein fractions for antirachitic activity. Owing to the low level of the vitamin in blood they had not enough material to subdivide the protein fractions, but they were able to show that it can all be found in the albumin and a-globulin regions. Similar results were obtained from human serum incubated in vitro with vitamin D.
No takes yet. Share an insight, caveat, or question.
Chalk et al. (1961) studied this question.
Synapse has enriched 5 related papers. Consider them for comparative context: