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January 1, 2000Thrombosis and Haemostasis

A Prospective Controlled Trial Comparing Weekly Self-testing and Self-dosing with the Standard Management of Patients on Stable Oral Anticoagulation

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Why the study?

Does weekly self-testing and self-dosing improve INR control in patients on stable oral anticoagulation compared to standard management?

Population

102 patients on stable oral anticoagulation for artificial heart valves, atrial fibrillation, or venous…

Comparison

Weekly self-testing and self-dosing of oral… vs Standard-management in an anticoagulation clinic

Design

Cohort

Authors

EFE. ForbergVienna General HospitalGSGerhard SvolbaUniversity of ViennaBKB KrinningerUniversity of Vienna

Discussion

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Implication

May support self-testing/self-dosing for better INR control in cohorts; hypothesis-generating and requires randomized confirmation before practice change.

Structured PICO

Does weekly self-testing and self-dosing improve INR control in patients on stable oral anticoagulation compared to standard management?

P
Population
102 patients on stable oral anticoagulation for artificial heart valves, atrial fibrillation, or venous thromboembolism (n=49 in self-management group, n=53 in standard-management group)
I
Intervention
Weekly self-testing and self-dosing (self-management) of oral anticoagulation
C
Comparator
Standard-management in an anticoagulation clinic
O
Outcome
Deviation from the target INR, the fraction of INR determinations within the preset therapeutic range, and the difference between the target INR and the actually achieved mean INRsurrogate

Weekly self-testing and self-dosing of oral anticoagulation leads to better INR control compared to standard management in an anticoagulation clinic.

Cite This Study

Forberg et al. (2000) studied this question.

synapsesocial.com/papers/6a7cc86e4ec837fd6928ac66https://doi.org/10.1055/s-0037-1613888

Topics

Anticoagulation in AF
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Long-term Patient Self-management of Oral Anticoagulation1995 · 175 citations
  2. 2Trial of Different Intensities of Anticoagulation in Patients with Prosthetic Heart Valves1990 · 371 citations
  3. 3Thrombotic and Hemorrhagic Complications in Patients with Mechanical Heart Valve Prosthesis Attending an Anticoagulation Clinic1993 · 157 citations
  4. 4Bleeding complications in oral anticoagulant therapy. An analysis of risk factors1993 · 539 citations
  5. 5Multicenter evaluation of a new capillary blood prothrombin time monitoring system1995 · 69 citations