Why the study?
Immune, neuroendocrine, and autonomic dysregulation in anorexia nervosa cause cardiovascular complications that can increase morbidity and mortality, warranting non-invasive tools for early diagnosis and monitoring.
Does nailfold video-capillaroscopy and autonomic assessment improve early diagnosis of cardiovascular involvement in patients with anorexia nervosa?
Does nailfold video-capillaroscopy and autonomic assessment improve early diagnosis of cardiovascular involvement in patients with anorexia nervosa?
Nailfold video-capillaroscopy and non-invasive autonomic assessment are recommended as promising tools for early diagnosis of cardiovascular complications in anorexia nervosa.
Autonomic assessment may flag cardiovascular risk in anorexia nervosa; leaves open clinical utility pending prospective validation.
Immune, neuroendocrine, and autonomic nervous system dysregulation in anorexia nervosa lead to cardiovascular complications that can potentially result in increased morbidity and mortality. It is suggested that a complex non-invasive assessment of cardiovascular autonomic regulation-cardiac vagal control, sympathetic vascular activity, and cardiovascular reflex control-could represent a promising tool for early diagnosis, personalized therapy, and monitoring of therapeutic interventions in anorexia nervosa particularly at a vulnerable adolescent age. In this view, we recommend to consider in the diagnostic route, at least in the subset of patients with peripheral microvascular symptoms, a nailfold video-capillaroscopy as an easy not invasive tool for the early assessing of possible cardiovascular involvement.
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Sirufo et al. (2021) studied this question.
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