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August 1, 1978NeurologyOpen Access

The Harvard Cooperative Stroke Registry

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Authors

JMJ.P. MohrBoston UniversityLCLouis R. CaplanUniversity of Arkansas at Little RockJMJohn W. MelskiMarshfield Clinic

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Implication

Prospective registry study reveals distinct subtype frequencies and clinical presentations in hospitalized stroke patients, highlighting atypical features in emboli and hematomas.

Key Points

  • To prospectively characterize stroke subtypes, their relative frequencies, and distinct clinical presentations using a computerized registry.
  • Prospective, computer-based clinical registry of N=694 patients hospitalized with stroke.
  • Categorized cases into thrombosis (large artery vs. lacunar infarction), cerebral embolism, intracerebral hematoma, and subarachnoid hemorrhage.
  • Stroke subtypes comprised thrombosis in 53% (34% large-artery, 19% lacunar infarction), cerebral embolism in 31%, intracerebral hematoma in 10%, and subarachnoid hemorrhage in 6%.
  • Cerebral emboli lacked an identifiable cardiac origin in 37% of cases and presented with a nonsudden onset in 21%.
  • Intracerebral hematomas presented with vomiting at onset in 51% of patients and lacked headache at onset in 67%.

Cite This Study

Mohr et al. (1978) studied this question.

synapsesocial.com/papers/6a7ccfdb3e26b190715bc4dchttps://doi.org/10.1212/wnl.28.8.754
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