February 22, 1993FEBS Letters

Molecular cloning of a novel rat G‐protein‐coupled receptor gene expressed prominently in lung, adrenal, and liver

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Population

Rat genomic library and rat liver cDNA library (adult rat tissues)

Design

Preclinical

Authors

JHJeffrey K. HarrisonDuke University CBCynthia M. BarberScripps Research Institute KLKevin R. LynchVascular Medicine

Discussion

Member takes

Implication

Provides novel rat GPCR target for lung/liver/adrenal studies; leaves open human ortholog function and disease relevance.

Structured PICO

Population

Rat genomic library and rat liver cDNA library (adult rat tissues)

Intervention

Molecular cloning, PCR amplification, hybridization screening, and Northern analysis

Outcome

Isolation and characterization of the G10d gene and mRNA distribution

The study identifies and characterizes a novel rat G-protein-coupled receptor gene, G10d, which is highly expressed in lung, liver, and adrenal tissues.

Cite This Study

Harrison et al. (1993) studied this question.

synapsesocial.com/papers/6a7cd50050edcffafcaeb082 https://doi.org/10.1016/0014-5793(93)81318-t

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Molecular cloning of a novel rat G‐protein‐coupled receptor gene expressed prominently in lung, adrenal, and liver

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Molecular cloning of a novel rat G‐protein‐coupled receptor gene expressed prominently in lung, adrenal, and liver

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider