Low Adiponectin Level Causes Vascular Remodeling?: A Perspective through Intravascular Ultrasound

Nissen SE, Tuzcu EM, Schoenhagen P, et al , REVERSAL Investigators: Effect of intensive compared with moderate lipid-lowering therapy on progression of coronary atherosclerosis: atherosclerosis: a randomized controlled trial. JAMA 2004; 291 : 1071–1080. Article CAS Google Scholar Berry C, L'Allier PL, Grégoire J, et al : Comparison of intravascular ultrasound and quantitative coronary angiography for the assessment of coronary artery disease progression. Circulation 2007; 115 : 1851–1857. Article Google Scholar Glagov S, Weisenberg E, Zarins CK, Stankunavicius R, Kolettis GJ : Compensatory enlargement of human atherosclerotic coronary arteries. N Engl J Med 1987; 316 : 1371–1375. Article CAS Google Scholar Nissen SE, Tuzcu EM, Libby P, et al , CAMELOT Investigators: Effect of antihypertensive agents on cardiovascular events in patients with coronary disease and normal blood pressure: the CAMELOT study: a randomized controlled trial. JAMA 2004; 292 : 2217–2225. Article CAS Google Scholar Katayama T, Kubo N, Takagi Y, et al : Relation of atherothrombosis burden and volume detected by intravascular ultrasound to angiographic no-reflow phenomenon during stent implantation in patients with acute myocardial infarction. Am J Cardiol 2006; 97 : 301–304. Article Google Scholar Iwata A, Miura S, Mori K, Kawahara A, Nishikawa H, Saku K : Associations between metabolic factors and coronary plaque growth or arterial remodeling as assessed by intravascular ultrasound in patients with stable angina. Hypertens Res 2008; 31 : 1879–1886. Article CAS Google Scholar Arita Y, Kihara S, Ouchi N, et al : Adipocyte-derived plasma protein adiponectin acts as a platelet-derived growth factor-BB–binding protein and regulates growth factor–induced common postreceptor signal in vascular smooth muscle cell. Circulation 2002; 105 : 2893–2898. Article CAS Google Scholar Wang Y, Lam KS, Xu JY, et al : Adiponectin inhibits cell proliferation by interacting with several growth factors in an oligomerization-dependent manner. J Biol Chem 2005; 280 : 18341–18347. Article CAS Google Scholar Matsuda M, Shimomura I, Sata M, et al : Role of adiponectin in preventing vascular stenosis. The missing link of adipo-vascular axis. J Biol Chem 2002; 277 : 37487–37491. Article CAS Google Scholar Chen ZP, Mitchelhill KI, Michell BJ, et al : AMP activated protein kinase phosphorylation of endothelial NO synthase. FEBS Lett 1999; 443 : 285–289. Article CAS Google Scholar Ouchi N, Kihara S, Arita Y, et al : Novel modulator for endothelial adhesion molecules: adipocyte-derived plasma protein adiponectin. Circulation 1999; 100 : 2473–2476. Article CAS Google Scholar Hopkins TA, Ouchi N, Shibata R, Walsh K : Adiponectin actions in the cardiovascular system. Cardiovasc Res 2007; 74 : 11–18. Article CAS Google Scholar Spranger J, Kroke A, Mohlig M, et al : Adiponectin and protection against type 2 diabetes mellitus. Lancet 2003; 361 : 226–228. Article CAS Google Scholar Lindsay RS, Resnick HE, Zhu J, et al : Adiponectin and coronary heart disease: the Strong Heart Study. Arterioscler Thromb Vasc Biol 2005; 25 : e15–e16. Article CAS Google Scholar Lawlor DA, Davey Smith G, Ebrahim S, Thompson C, Sattar N : Plasma adiponectin levels are associated with insulin resistance, but do not predict future risk of coronary heart disease in women. J Clin Endocrinol Metab 2005; 90 : 5677–5683. Article CAS Google Scholar Sattar N, Wannamethee G, Sarwar N, Tchemova J, Cherry L, Wallace AM : Adiponectin and coronary heart disease: a prospective study and meta-analysis. Circulation 2006; 114 : 623–629. Article CAS Google Scholar Kistorp C, Faber J, Galatius S, et al : Plasma adiponectin, body mass index, and mortality in patients with chronic heart failure. Circulation 2005; 112 : 1756–1762. Article CAS Google Scholar Nakamura T, Funayama H, Kubo N, et al : Association of hyperadiponectinemia with severity of ventricular dysfunction in congestive heart failure. Circ J 2006; 70 : 1557–1562. Article Google Scholar Wannamethee SG, Whincup PH, Lennon L, Sattar N : Circulating adiponectin levels and mortality in elderly men with and without cardiovascular disease and heart failure. Arch Intern Med 2007; 167 : 1510–1517. Article CAS Google Scholar Menon V, Li L, Wang X, et al : Adiponectin and mortality in patients with chronic kidney disease. J Am Soc Nephrol 2006; 17 : 2599–2606. Article CAS Google Scholar Download references