Why the study?
Massive pericardial effusion typically progresses to cardiac tamponade with hypotension rather than high blood pressure, making presentation with hypertensive emergency rare.
Profound hypothyroidism can rarely present with massive pericardial effusion and hypertensive emergency, requiring careful blood pressure management and pericardiocentesis.
May prompt thyroid evaluation in hypertensive emergency with effusion; hypothesis-generating for atypical tamponade physiology.
BACKGROUND Thyroid function is closely related to the cardiovascular system. Pericardial effusion is a well-known complication of hypothyroidism. It is common for massive pericardial effusion to progress to tamponed heart with hypotension, but not high blood pressure. CASE REPORT A 46-year-old woman presented to the hospital with dysarthria and left-side weakness of the upper limb which had started 30 minutes before her arrival at the hospital. The patient showed hypertensive emergency (213/124 mmHg) with intracerebral hemorrhage. Further evaluation for high blood pressure and transthoracic echocardiography demonstrated the presence of a large amount of pericardial effusion, and urgent pericardiocentesis was performed. The laboratory examination showed elevated thyroid-stimulating hormone and decreased free thyroxine level, leading to a diagnosis of primary hypothyroidism. The administration of current medications was maintained, including thyroid hormone replacement and anti-hypertensive drugs. CONCLUSIONS A rare case of profound hypothyroidism presenting with hypertensive crisis and massive pericardial effusion is described in this report.
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Ji‐won Hwang (2020) studied this question.
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